With just a handful of games left, but many important points to play for, now is the time for teams with their eyes firmly on the top table to mount that final charge.
Of course, a rampant Manchester City can be found flying high at the top of the standings and are guaranteed a spot in the competition next season. The same stands for Manchester United with their hefty 11-point advantage over fifth spot.
The hotly-contested race for the Champions League is set to go down to the wire this season
Chelsea have found superb form under boss Thomas Tuchel and currently occupy fourth place
But for the rest of the challengers, their fate is firmly up in the air. Leicester and Chelsea will be confident, but stranger collapses have happened in the top-flight.
Here, Sportsmail takes a look at the runners and riders and assesses their chances of a top four finish…
3RD – LEICESTER (63 POINTS)
What a season this has been from Brendan Rodgers’ high-flyers. They will be hoping it doesn’t end here, though and they have a tricky run-in to cement their place in the top four.
The former champions are sitting pretty in a very good position, seven points clear of fifth and unbeaten in their last three games.
However, it is far from a done deal and their final few matches will prove decisive over whether they can banish the demons of the late slip-up last campaign.
Up next is Newcastle, and Leicester head into that clash with all guns blazing in search of three more invaluable points.
Leicester are flying high in third spot and will want to avoid a late collapse like last campaign
Brendan Rodgers will have to guide his team through a very testing set of fixtures this month
After that, they face a trip to Manchester United, currently the team above them, before a showdown with fellow Champions League contenders Chelsea.
Their final fixture sees them welcome Tottenham, yet another team knocking on the door of the top spots.
A win against Newcastle and points taken off any of the other teams stacked up behind them will surely see Leicester get over the line this time around.
Their swaggering and passionate displays mean that a return to the elite club competition will be more than merited.
LEICESTER’S FINAL FIXTURES
May 7 – Newcastle (H)
May 12 – Manchester United (A)
May 19 – Chelsea (A)
May 23 – Tottenham (H)
4TH – CHELSEA (61 POINTS)
Thomas Tuchel has performed miracles since replacing Frank Lampard with Chelsea in the FA Cup final, Champions League semi-finals and now back in the top four.
They do find themselves in the same situation as Leicester, however, with a number of mouth-watering clashes holding the potential to mar the end of the season.
Following their second leg encounter with Real Madrid, an in-form Chelsea travel to champions-in-waiting City. A defeat there would open the door for their rivals.
Thomas Tuchel has performed miracles at Chelsea and a top four finish would be a success
Chelsea eased to a win against Fulham and remain in full control of their own destiny in fourth
After that, a London derby against Arsenal at Stamford Bridge awaits, before fixtures against the Foxes and Aston Villa.
Their destiny is truly in their own hands and a rampant run of form sees them strong favourites to, at the very least, keep a tight grip on fourth.
Avoiding a loss at the Etihad, followed by a win against Arsenal, is likely to be enough to cap off a deserved end to their domestic campaign.
Success in Europe and at Wembley would then turn a great season into a truly outstanding one.
CHELSEA’S FINAL FIXTURES
May 8 – Manchester City (A)
May 12 – Arsenal (H)
May 19 – Leicester (H)
May 23 – Aston Villa (A)
5TH – TOTTENHAM (56 POINTS)
Where have Tottenham come from? Ryan Mason will have quite simply performed heroics if he leads his team into the Champions League.
The sacking of Jose Mourinho was no shock, but the timing was undoubtedly surprising. However, a late push for fourth would see the decision pay off in spades.
Currently, it does appear unlikely. The improved showings against Southampton and Sheffield United handed them six key points, but it may already be too little, too late.
Up next are four more games, all equally as crucial as the next. Anything less than three wins is certain to see them slide into the Europa League once again.
Gareth Bale hit a hat-trick against Sheffield United and kept Tottenham in top four contention
Ryan Mason (L) was given the reins until the end of the season after Jose Mourinho’s (R) axing
On May 8, a testing trip to Leeds looms large. As many of Tottenham’s big-name rivals have found out, Elland Road is usually an unwelcoming and harsh venue.
Despite this, a win is needed. After that, rookie Mason will guide his team through home clashes against Wolves and Aston Villa.
With both teams in the bottom half, Tottenham must capitalise. Depending on the results of the clubs pushing for fourth, three wins would set Spurs in good stead.
A final day visit to Leicester then rounds off the season. It may very well prove that they both need the points to avoid heartbreak, or that the race is already over.
TOTTENHAM’S FINAL FIXTURES
May 8 – Leeds (A)
May 16 – Wolves (H)
May 19 – Aston Villa (H)
May 23 – Leicester (A)
6TH – WEST HAM (55 POINTS)
The chance is there for West Ham to do what seemed impossible – end up in the Champions League next season. Be honest, who saw that coming?
Two chastening defeats, with one coming against Chelsea, may have dented their aspirations but their inspiring journey is not over. Far from it, in fact.
They are one of the contenders who hold a game in hand over the teams above them, and a win against Burnley this evening will see the gap close to three points.
A triumph at Turf Moor would also have a positive mental impact, sending them into their final four games with fresh impetus. There can be no more setbacks.
West Ham have stuttered in their unlikely top four charge but will hope for last-gasp heroics
David Moyes has rightly earned plenty of plaudits this season with West Ham still in the race
On May 9, West Ham take on Everton, a team with just one victory in five and stuttering towards the finish line.
Then, they face Brighton, West Brom and Southampton. All three clubs find themselves at the wrong end of the table and West Ham will sense an opportunity.
It is one they must pounce on. Brighton will prove stern opposition and are far better than their position suggests.
But West Brom and Southampton are scrabbling for points for a reason. At least four wins will be needed for West Ham, and the chances are there. Will they take them?
WEST HAM’S FINAL FIXTURES
May 3 – Burnley (A)
May 9 – Everton (H)
May 15 – Brighton (A)
May 19 – West Brom (A)
May 23 – Southampton (H)
7TH – LIVERPOOL (54 POINTS)
This has been a painful and bitter campaign for the fallen champions. Their title defence is officially over, and the crown is destined for City sooner rather than later.
All that remains now is a finish in the Champions League spots – and even that is looking unlikely based on the current state of play.
They are unbeaten in five, but the two recent draws against Newcastle and Leeds are effectively a microcosm of their season – missed chances and disappointment.
To defy the odds and end up in fourth, Liverpool must do what they haven’t managed to do all season: be consistent. They have five games to do it.
Liverpool have endured a nightmare season after a failed title defence and sit in seventh spot
Jurgen Klopp will be hoping his team are able to salvage their campaign with a top four finish
One of those, of course, comes against fierce rivals Manchester United. That was meant to happen yesterday, but protests at Old Trafford saw it postponed.
It is unclear when the game will now be played, but there are four other games in the meantime that Liverpool must take maximum points from.
Provided their forwards, namely Sadio Mane and Roberto Firmino, step up, they are likely to live up to their side of the bargain.
Jurgen Klopp’s men take on Southampton, West Brom, Burnley and Crystal Palace. On paper, they should come out on top but no top-flight games are easy.
Taking points off United will also aid their cause. If they don’t, that will likely spell the end of their season anyway.
LIVERPOOL’S FINAL FIXTURES
May 8 – Southampton (H)
May 16 – West Brom (A)
May 19 – Burnley (A)
May 23 – Crystal Palace (H)
TBC – Manchester United (A)
8TH – EVERTON (52 POINTS)
Everton remain delightfully inconsistent. They are enthralling to watch for neutrals, but their mixed form may well have already put an end to their top four hopes.
The sole win in their last five encapsulates their quandary perfectly. Bizarrely, that came at Arsenal – pointing towards their ability to beat the so-called ‘Big Six’.
However, they are failing to go toe-to-toe with those teams. Far too many slip-ups and mistakes against teams below them have proven their downfall.
They must leave this tendency in the past and go full throttle to make up the nine-point gap currently between them and Chelsea.
Everton’s inconsistency this season has all but derailed their ambitions of a top finish finish
Carlo Ancelotti will know his team must avoid more slip-ups with fixtures rapidly running out
Following their limp home loss to Aston Villa, Everton travel to West Ham.
A Hammers defeat tonight, followed by an Everton win against them, would help Carlo Ancelotti’s charges move level on 55 points.
After that, Everton travel to Villa and will need all three points to avenge Saturday’s punishing result.
Two home clashes quickly follow against Sheffield United and Wolves – before Manchester City await at the end of the campaign.
Similarly to the three teams above them, even a draw may be enough to see them miss out. A big final push is needed.
EVERTON’S FINAL FIXTURES
May 9 – West Ham (A)
May 13 – Aston Villa (A)
May 16 – Sheffield United (H)
May 19 – Wolves (H)
May 23 – Manchester City (A)