The Blues stamped their authority on proceedings early on at Madrid’s Alfredo Di Stefano Stadium – where they played with the Santiago Bernabeu currently under renovation – with Christian Pulisic giving the visitors a 14th-minute lead.
However, against the run of play, Karim Benezma spectacularly volleyed home an equaliser to set up a mouth-watering encounter in London.
The eventual winner will go onto face Manchester City in May’s final, after Pep Guardiola’s side beat Paris Saint-Germain 2-0 at the Etihad on Tuesday to seal a 4-1 aggregate win and a place in the Champions League final for the first time.
With the highly-anticipated spectacle now quickly approaching, Sportsmail takes you through the all-important information.
Thomas Tuchel (left) and Zinedine Zidane (right) go head-to-head once more on Wednesday
When is Chelsea vs Real Madrid?
Chelsea host Real Madrid in their Champions League semi-final second leg on Wednesday, May 5.
The match will kick-off at 8pm BST at Stamford Bridge and will be played behind closed doors due to the prevalent coronavirus restrictions.
After a highly competitive first leg, a Kai Havertz double gave Chelsea an important 2-0 win over Fulham in the Premier League, edging them further towards a top-four finish.
Meanwhile, Madrid claimed a hugely important 2-0 win over Osasuna, though they remain two points behind La Liga leaders Atletico Madrid with just four games to play.
How to watch the Champions League semi-final
The match will be broadcast live on BT Sport 2, with coverage getting underway at 7pm.
Subscribers can also watch the game on both the BT website and app.
Tuchel has confirmed that Mateo Kovacic will miss the Madrid clash with a hamstring injury
Sergio Ramos is fit to play having missed out on the last 10 matches, including the first leg
Thomas Tuchel has the majority of his squad available to face Madrid, with the one absentee being Mateo Kovacic, who has failed to recover from a hamstring injury.
Defender Antonio Rudiger had been a doubt, but Tuchel has confirmed he is set to play, though wearing a protective mask having suffered an injury to his face in the first leg.
Tuchel has a number of decisions to make ahead of the all-important clash, with Havertz providing a timely reminder of his quality with his double against Palace.
Meanwhile, Tuchel has admitted that Timo Werner’s struggles in front of goal are an issue, though insisting the German will improve with experience and added confidence.
As for Madrid, they will be without right-back pair Dani Carvajal and Lucas Vasquez, while Raphael Varane has also been ruled out.
However, they have received a boost by the return of captain Sergio Ramos, who has missed the last 10 games, including the first leg.
They will also have both Fede Valverde and Marcelo available, the latter of whom has been released from his call-up for election duty.
Eden Hazard is also set to make his return to Stamford Bridge, having played 70 minutes on Saturday.
Chelsea vs Madrid: The odds
Chelsea will come into the encounter full of confidence after a promising performance in the first leg.
They remain unbeaten in their four matches against the Spaniards, and come into the fixture as the favourites among the bookies, with odds of 8/13 to reach the final.
With all of their experience, it would be no surprise if Madrid did come away with the win, but they’re the underdogs heading into the clash, with odds of 5/4 to reach the final two.
*Odds as per Betfair and correct at the time of publication.
Champions League semi-finals
Tuesday, April 27
- Real Madrid 1-1 Chelsea
Wednesday, April 28
- Paris Saint-Germain 1-2 Manchester City
Tuesday, May 4
- Manchester City 2-0 Paris Saint-Germain
Wednesday May 5
- Chelsea vs Real Madrid